Name: JWH-073 JWH-200 JWH-250
SKU: 23659
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JWH-073 JWH-200 JWH-250

Unlike many of the older JWH series compounds, this compound does not have a naphthalene ring, instead occupying this position with a 2′-methoxy-phenylacetyl group, making JWH-250 a representative member of a new class of cannabinoid ligands.

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JWH-073 JWH-200 JWH-250. JWH-250, also known as (1-pentyl-3-(2-methoxyphenylacetyl)indole), is a cannabinoid agonist that works on both the CB1 and CB2 receptors. It has a Ki of 11 nM at CB1 and 33 nM at CB2.

Huffman. He developed JWH-250 and other chemicals to study the endocannabinoid system of mammals.

JWH-073, JWH-200 are all chemical compounds that act as cannabinoid agonists:

JWH-250

A phenylacetylindole family analgesic chemical with a molar mass of 335.44 g/mol.

JWH-200

An aminoalkylindole family analgesic chemical with a molar mass of 384.47 g/mol. It acts as a cannabinoid receptor agonist.

JWH-073, and JWH-250 are all chemical compounds that act as cannabinoid agonists:

Cannabinoids and their K_i values^[a]
Name	Class	K_i / nM at CB₁	K_i / nM at CB₂	Selectivity
JWH-004	Naphthoylindole	48 ± 13	4 ± 1.5	CB₂ (12x)
JWH-007^[5]	Naphthoylindole	9.5 ± 4.5	2.9 ± 2.6	CB₂ (3.3x)
JWH-009	Naphthoylindole	>10000	141 ± 14	CB₂ (>70x)
JWH-011	Naphthoylindole
JWH-015^[5]	Naphthoylindole	164 ± 22	13.8 ± 4.6	CB₂ (12x)
JWH-016	Naphthoylindole	22 ± 1.5	4.3 ± 1.6	CB₂ (5.1x)
JWH-018^[5]	Naphthoylindole	9 ± 5	2.9 ± 2.6	CB₂ (3.1x)
JWH-019	Naphthoylindole	9.8 ± 2	5.55 ± 2	CB₂ (1.77x)
JWH-020	Naphthoylindole	128 ± 17	205 ± 20	CB₁ (1.6x)
JWH-030	Naphthoylpyrrole	87 ± 3	320 ± 127	CB₁ (3.7x)

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Cannabinoids and their K_i values^[a]
Name	Class	K_i / nM at CB₁	K_i / nM at CB₂	Selectivity
JWH-004	Naphthoylindole	48 ± 13	4 ± 1.5	CB₂ (12x)
JWH-007^[5]	Naphthoylindole	9.5 ± 4.5	2.9 ± 2.6	CB₂ (3.3x)
JWH-009	Naphthoylindole	>10000	141 ± 14	CB₂ (>70x)
JWH-011	Naphthoylindole
JWH-015^[5]	Naphthoylindole	164 ± 22	13.8 ± 4.6	CB₂ (12x)
JWH-016	Naphthoylindole	22 ± 1.5	4.3 ± 1.6	CB₂ (5.1x)
JWH-018^[5]	Naphthoylindole	9 ± 5	2.9 ± 2.6	CB₂ (3.1x)
JWH-019	Naphthoylindole	9.8 ± 2	5.55 ± 2	CB₂ (1.77x)
JWH-020	Naphthoylindole	128 ± 17	205 ± 20	CB₁ (1.6x)
JWH-030	Naphthoylpyrrole	87 ± 3	320 ± 127	CB₁ (3.7x)